January 24, 2025 • 2hr 41min

#2262 - Dr. Mark Gordon

The Joe Rogan Experience

Dr. Mark Gordon returns to the Joe Rogan Experience podcast after a 4-year hiatus. He is a neuroendocrinologist focused on treating traumatic brain injuries and PTSD, particularly in veterans, through hormone optimization and reducing neuroinflammation. The wide-ranging conversation covers advances in his treatment protocols, consciousness, unexplained phenomena, and maintaining health as we age.

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Key Takeaways

Brain Health & Inflammation: Dr. Gordon emphasizes that inflammation in the brain is a key driver of mental health issues and cognitive decline. Reducing inflammation through supplements, hormones and lifestyle changes is critical.
Hormone Optimization: Maintaining optimal hormone levels through replacement therapy, especially as we age, is essential for mental and physical wellbeing. Dr. Gordon credits his clarity and functionality at age 72 to 30 years of hormone replacement.
Nutritional Supplementation: Taking targeted supplements like quercetin, glutathione, omega-3s and others helps combat inflammation and supports brain health. The idea that you can get everything you need from diet alone is "horseshit."
Veterans' Mental Health: Dr. Gordon's work focuses on helping veterans with TBI and PTSD through a comprehensive protocol involving hormones, supplements and other treatments to reduce brain inflammation.
Consciousness & Reality: Extended discussion about UFOs, aliens, and unexplained phenomena suggests reality may be stranger than we understand, with consciousness potentially able to interact with other dimensions.

Introduction

Dr. Mark Gordon returns to the Joe Rogan Experience podcast after a 4-year hiatus. He is a neuroendocrinologist focused on treating traumatic brain injuries and PTSD, particularly in veterans, through hormone optimization and reducing neuroinflammation. The wide-ranging conversation covers advances in his treatment protocols, consciousness, unexplained phenomena, and maintaining health as we age.

Topics Discussed

Brain Inflammation & Treatment Protocols (1:52)

Dr. Gordon explains how his understanding and treatment of brain inflammation has evolved over the past 30 years. The core premise remains that inflammation disrupts brain chemistry and leads to various symptoms.

New additions to protocol include more nootropics and natural products that can cross the blood-brain barrier
Media-induced stress increases cortisol and shuts down protective brain chemicals like fractalkin
Inflammation disrupts serotonin and melatonin production, affecting mood and sleep
Treatment focuses on reducing inflammation while optimizing hormones that protect the brain

Nutritional Supplementation & Optimization (33:52)

The discussion turns to the importance of nutritional supplementation, with Dr. Gordon emphasizing that relying on diet alone is insufficient for optimal health.

Key supplements include quercetin, glutathione, omega-3s, B vitamins, and CoQ10
Quercetin benefits: Acts as zinc ionophore, increases mitochondrial function, anti-viral properties
Doctors often lack comprehensive understanding of nutrition and supplementation
Personal experience shows marked difference when consistently taking supplements vs not

Hormone Optimization & Aging (1:27:34)

Dr. Gordon shares his perspective on hormone optimization and maintaining vitality as we age, drawing from personal experience.

30 years of hormone replacement therapy key to maintaining clarity and functionality at 72
Common misconception that aging naturally means accepting decline
Exercise remains crucial for maintaining physical presence and bone density
Combination approach: hormones, supplements, exercise for optimal results

Consciousness & Alternative Realities (2:02:57)

The conversation explores consciousness, UFOs, and the possibility of other dimensions or forms of intelligence.

Reality may be more complex than our senses can detect
Dreams and consciousness could potentially access other dimensions
UFO phenomena might involve advanced technology or interdimensional beings
Human understanding of consciousness and reality may be limited

Technology & Privacy Concerns (2:33:49)

Discussion of advancing technology and its implications for privacy and security.

Quantum computing threatens current encryption methods
WiFi signals can now be used to create 3D representations of people in rooms
Increasing surveillance and data collection raise privacy concerns
Alternative technologies like de-Googled phones offer some protection

Conclusion

The episode concludes with Dr. Gordon emphasizing the importance of his work with veterans and promoting science-based approaches to brain health and longevity. He mentions his involvement with the Biohack Yourself program and collaboration with Robert F. Kennedy Jr.'s team to promote legitimate science.

Key resources mentioned include:

Website: TBIHelpNow.org
Warrior Angels Foundation
Biohack Yourself program

The conversation demonstrates how integrative approaches to health, combining hormone optimization, supplementation, and lifestyle factors, can support cognitive function and overall wellbeing as we age. It also highlights the importance of remaining open-minded about consciousness and reality while maintaining scientific rigor in treatment approaches.